Manufacturing sales rose 2.6% to $49.2 billion in September, their third straight monthly increase.
Statistics Canada reports the gain largely reflected higher sales in the petroleum and coal products and transportation equipment industries.
Constant-dollar manufacturing sales were up 1.8%.
Higher sales were reported in 10 of 21 industries, representing 60.5% of total manufacturing.
Sales of petroleum and coal products rose 13.7% to $7.6 billion in September, their largest percentage increase since March 1999, while transportation equipment sales rose 7.1% to $8.0 billion.
The September increase was partly offset by a 3.0% decline in food industry sales.
Stronger manufacturing sales were reported in nine provinces in September, with Alberta, Quebec, New Brunswick and Ontario leading the way.
New orders rose 4.8% to $51.0 billion in September.